Selected Publications
2025
- LSGI: interpretable spatial gradient analysis for spatial transcriptomics data.
Liang, Q., Soto, L.S., Haymaker, C., and Chen, K. Genome Biology 26, 238 (2025). - Depletion of effector regulatory T cells associates with major response to induction dual immune checkpoint blockade.
Jiang, X., Rudqvist, N.P., Jiang, B., … et al. Cancer Discovery 15(8), pp.1569–1592 (2025). - CREM is a regulatory checkpoint of CAR and IL-15 signalling in NK cells.
Rafei, H., Basar, R., Acharya, S., … et al. Nature 643(8073), pp.1076–1086 (2025).
2024
- Stem cell activity-coupled suppression of endogenous retrovirus governs adult tissue regeneration.
Lyu, Y., Kim, S.J., Humphrey, E.S., … et al. Cell 187(26), pp.7414–7432 (2024).
2023
- Pathway centric analysis for single-cell RNA-seq and spatial transcriptomics data with GSDensity.
Liang, Q., Huang, Y., He, S., and Chen, K. Nature Communications 14, 1–17 (2023). - Single-cell multiomics of the human retina reveals hierarchical transcription factor collaboration in mediating cell type-specific effects of genetic variants on gene regulation.
Wang, J., Cheng, X., Liang, Q., … et al. Genome Biology 24(1), p.269 (2023). - A multi-omics atlas of the human retina at single-cell resolution.
Liang, Q., Cheng, X., Wang, J., … et al. Cell Genomics 3, 100298 (2023). - Spatial organization of the mouse retina at single cell resolution by MERFISH.
Choi, J., Li, J., Ferdous, S., Liang, Q., Moffitt, J.R., and Chen, R. Nature Communications 14(1), p.4929 (2023).
2022
- Bi-order multimodal integration of single-cell data.
Dou, J., Liang, S., Mohanty, V., … et al. Genome Biology 23(1), p.112 (2022).
2021
- Transcript isoforms of Reep6 have distinct functions in the retina.
Liang, Q., Wu, N., Zaneveld, S., … et al. Human Molecular Genetics 30, 1907–1918 (2021).
2019
- Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling.
Liang, Q., Dharmat, R., Owen, L., … et al. Nature Communications 10, 1–12 (2019). - A nonhuman primate model of inherited retinal disease.
Moshiri, A., Chen, R., Kim, S., … et al. The Journal of Clinical Investigation 129(2), pp.863–874 (2019).
2015
- Structural insights on the catalytic site protection of human carbonyl reductase 1 by glutathione.
Liang, Q., Liu, R., Du, S., and Ding, Y. Journal of Structural Biology 192, 138–144 (2015).
For complete list of publications, see Google Scholar.